The human VRK1 chromatin kinase in cancer biology
VRK1 is a nuclear Ser-Thr chromatin kinase that does not mutate in cancer, and is overexpressed in many types of tumors and associated with a poor prognosis. Chromatin VRK1 phosphorylates several transcription factors, including p53, histones and proteins implicated in DNA damage response pathways....
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Revisão |
| Language: | English |
| Published: |
2021
|
| Online Access: | https://doi.org/10.1016/j.canlet.2020.12.032 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|