The human VRK1 chromatin kinase in cancer biology

The human VRK1 chromatin kinase in cancer biology

VRK1 is a nuclear Ser-Thr chromatin kinase that does not mutate in cancer, and is overexpressed in many types of tumors and associated with a poor prognosis. Chromatin VRK1 phosphorylates several transcription factors, including p53, histones and proteins implicated in DNA damage response pathways....

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Bibliografske podrobnosti
Main Authors:	Ignacio Campillo‐Marcos, Raúl García-González, Elena Navarro-Carrasco, Pedro A. Lazo
Format:	Revisão
Jezik:	angleščina
Izdano:	2021
Online dostop:	https://doi.org/10.1016/j.canlet.2020.12.032
Oznake:	Označite Brez oznak, prvi označite!

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