Identification of a subset of immunosuppressive P2RX1-negative neutrophils in pancreatic cancer liver metastasis

Identification of a subset of immunosuppressive P2RX1-negative neutrophils in pancreatic cancer liver metastasis

Abstract The immunosuppressive microenvironment that is shaped by hepatic metastatic pancreatic ductal adenocarcinoma (PDAC) is essential for tumor cell evasion of immune destruction. Neutrophils are important components of the metastatic tumor microenvironment and exhibit heterogeneity. However, th...

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Main Authors: Xu Wang, Li-Peng Hu, Weiting Qin, Qin Yang, Deyu Chen, Qing Li, Kaixia Zhou, Pei-Qi Huang, Chunjie Xu, Jun Li, Linli Yao, Yahui Wang, Guang-Ang Tian, Jian‐Yu Yang, Minwei Yang, Dejun Liu, Yongwei Sun, Shu‐Heng Jiang, Xueli Zhang, Zhigang Zhang
Format: Artigo
Language:English
Published: 2021
Online Access:https://doi.org/10.1038/s41467-020-20447-y
https://www.nature.com/articles/s41467-020-20447-y.pdf
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https://doi.org/10.1038/s41467-020-20447-y
https://www.nature.com/articles/s41467-020-20447-y.pdf

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