An immune cocktail therapy to realize multiple boosting of the cancer-immunity cycle by combination of drug/gene delivery nanoparticles

Immune checkpoint blockade therapy (ICT) has shown potential in the treatment of multiple tumors, but suffers poor response rate in clinic. We found that even combining ICT with chemotherapy, which was wildly used in clinical trials, failed to achieve satisfactory tumor inhibition in the B16F10 mode...

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Main Authors: Jiayan Wu, Jie Chen, Yuanji Feng, Sijia Zhang, Lin Lın, Zhaopei Guo, Pingjie Sun, Caina Xu, Huayu Tian, Xuesi Chen
格式: Artigo
語言:英语
出版: 2020
在線閱讀:https://doi.org/10.1126/sciadv.abc7828
https://www.science.org/doi/pdf/10.1126/sciadv.abc7828?download=true
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