An immune cocktail therapy to realize multiple boosting of the cancer-immunity cycle by combination of drug/gene delivery nanoparticles

Immune checkpoint blockade therapy (ICT) has shown potential in the treatment of multiple tumors, but suffers poor response rate in clinic. We found that even combining ICT with chemotherapy, which was wildly used in clinical trials, failed to achieve satisfactory tumor inhibition in the B16F10 mode...

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Главные авторы: Jiayan Wu, Jie Chen, Yuanji Feng, Sijia Zhang, Lin Lın, Zhaopei Guo, Pingjie Sun, Caina Xu, Huayu Tian, Xuesi Chen
Формат: Artigo
Язык:английский
Опубликовано: 2020
Online-ссылка:https://doi.org/10.1126/sciadv.abc7828
https://www.science.org/doi/pdf/10.1126/sciadv.abc7828?download=true
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