A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes

Abstract Highly reproducible smoking-associated DNA methylation changes in whole blood have been reported by many Epigenome-Wide-Association Studies (EWAS). These epigenetic alterations could have important implications for understanding and predicting the risk of smoking-related diseases. To this e...

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Bibliografiske detaljer
Main Authors: Chenglong You, Sijie Wu, Shijie Zheng, Tianyu Zhu, Jing Han, Ken Flagg, Guangyu Wang, Jin Li, Sijia Wang, Andrew E. Teschendorff
Format: Revisão
Sprog:engelsk
Udgivet: 2020
Online adgang:https://doi.org/10.1038/s41467-020-18618-y
https://www.nature.com/articles/s41467-020-18618-y.pdf
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