Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma

Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma

BACKGROUNDPatients with diffuse midline gliomas (DMGs), including diffuse intrinsic pontine glioma (DIPG), have dismal outcomes. We previously described the H3.3K27M mutation as a shared neoantigen in HLA-A*02.01+, H3.3K27M+ DMGs. Within the Pacific Pediatric Neuro-Oncology Consortium, we assessed t...

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Main Authors: Sabine Mueller, Jared Taitt, Javier Villanueva-Meyer, Erin R. Bonner, Takahide Nejo, Rishi Lulla, Stewart Goldman, Anu Banerjee, Susan Chi, Nicholas Whipple, John R. Crawford, Karen Gauvain, Kellie J. Nazemi, Payal Watchmaker, Neil D. Almeida, Kaori Okada, Andres Μ. Salazar, Ryan Gilbert, Javad Nazarian, Annette M. Molinaro, Lisa H. Butterfield, Michael D. Prados, Hideho Okada
Format: Artigo
Language:English
Published: 2020
Online Access:https://doi.org/10.1172/jci140378
http://www.jci.org/articles/view/140378/files/pdf
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https://doi.org/10.1172/jci140378
http://www.jci.org/articles/view/140378/files/pdf

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