Complement activation on endothelium initiates antibody-mediated acute lung injury
Antibodies targeting human leukocyte antigen (HLA)/major histocompatibility complex (MHC) proteins limit successful transplantation and transfusion, and their presence in blood products can cause lethal transfusion-related acute lung injury (TRALI). It is unclear which cell types are bound by these...
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Hauptverfasser: | , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Englisch |
Veröffentlicht: |
2020
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Online-Zugang: | https://doi.org/10.1172/jci138136 http://www.jci.org/articles/view/138136/files/pdf |
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