<i>In vitro</i> and <i>in vivo</i> identification of clinically approved drugs that modify <i> <scp>ACE</scp> 2 </i> expression

The COVID-19 pandemic caused by SARS-CoV-2 has is a global health challenge. Angiotensin-converting enzyme 2 (ACE2) is the host receptor for SARS-CoV-2 entry. Recent studies have suggested that patients with hypertension and diabetes treated with ACE inhibitors (ACEIs) or angiotensin receptor blocke...

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Main Authors: Sanju Sinha, Kuoyuan Cheng, Alejandro A. Schäffer, Kenneth Aldape, Eyal Schiff, Eytan Ruppin
Formato: Artigo
Idioma:inglés
Publicado: 2020
Acceso en liña:https://doi.org/10.15252/msb.20209628
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