P2X7 Receptor Activity Limits Accumulation of T Cells within Tumors

P2X7 Receptor Activity Limits Accumulation of T Cells within Tumors

Extracellular ATP (eATP) is a signaling molecule that variably affects all cells of the immune system either directly or after hydrolysis to adenosine. Although eATP is virtually absent in the interstitium of normal tissues, it can be present in the hundreds of micromolar range in tumors, a concentr...

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Hlavní autoři: Andrea Romagnani, Elsa Rottoli, Emilia Maria Cristina Mazza, Tanja Rezzonico-Jost, Benedetta De Ponte Conti, Michele Proietti, Michela Perotti, Elisa Civanelli, Lisa Perruzza, Alberico L. Catapano, Andrea Baragetti, Elena Tenedini, Enrico Tagliafico, Simonetta Falzoni, Francesco Di Virgilio, Giuseppe Danilo Norata, Silvio Bicciato, Fabio Grassi
Médium: Artigo
Jazyk:angličtina
Vydáno: 2020
On-line přístup:https://doi.org/10.1158/0008-5472.can-19-3807
https://aacrjournals.org/cancerres/article-pdf/80/18/3906/2797359/3906.pdf
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Internet

https://doi.org/10.1158/0008-5472.can-19-3807
https://aacrjournals.org/cancerres/article-pdf/80/18/3906/2797359/3906.pdf

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