An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

Wedi'i Gadw mewn:

Manylion Llyfryddiaeth
Prif Awduron:	Vincent Debruycker, Andrew Hutchin, Matthieu Masureel, Emel Ficici, Chloé Martens, Pierre Legrand, Richard A. Stein, Hassane S. Mchaourab, José D. Faraldo‐Gómez, Han Remaut, Cédric Govaerts
Fformat:	Artigo
Iaith:	Saesneg
Cyhoeddwyd:	2020
Mynediad Ar-lein:	https://doi.org/10.1038/s41594-020-0464-y
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg

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Lipids modulate the conformational dynamics of a secondary multidrug transporter
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Basic Residues R260 and K357 Affect the Conformational Dynamics of the Major Facilitator Superfamily Multidrug Transporter LmrP
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Dynamic multidrug recognition by multidrug transcriptional repressor LmrR
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Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition
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Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity
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Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity
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Bacillus subtilis LmrA Is a Repressor of the lmrAB and yxaGH Operons: Identification of Its Binding Site and Functional Analysis of lmrB and yxaGH
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Serum PLR and LMR in Behçet's disease
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Dynamic equilibrium on DNA defines transcriptional regulation of a multidrug binding transcriptional repressor, LmrR
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LmrS Is a Multidrug Efflux Pump of the Major Facilitator Superfamily from <i>Staphylococcus aureus</i>
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Allosteric regulation of G protein–coupled receptor activity by phospholipids
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The molecular basis for a polyspecific antibody.
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Characterization of murine polyspecific monoamine transporters
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OCT1 Polyspecificity—Friend or Foe?
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Evidence of Calcium Signaling and Modulation of the LmrS Multidrug Resistant Efflux Pump Activity by Ca(2 +) Ions in S. aureus
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Structure, Dynamics, and Substrate-induced Conformational Changes of the Multidrug Transporter EmrE in Liposomes
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