An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity

Guardat en:

Dades bibliogràfiques
Autors principals:	Vincent Debruycker, Andrew Hutchin, Matthieu Masureel, Emel Ficici, Chloé Martens, Pierre Legrand, Richard A. Stein, Hassane S. Mchaourab, José D. Faraldo‐Gómez, Han Remaut, Cédric Govaerts
Format:	Artigo
Idioma:	anglès
Publicat:	2020
Accés en línia:	https://doi.org/10.1038/s41594-020-0464-y
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars

An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity
per: Debruycker, Vincent, et al.
Publicat: (2020)

Protonation drives the conformational switch in the multidrug transporter LmrP
per: Matthieu Masureel, et al.
Publicat: (2013)

Interactions between Phosphatidylethanolamine Headgroup and LmrP, a Multidrug Transporter
per: Pierre Hakizimana, et al.
Publicat: (2008)

AlphaFold2 predicts the inward-facing conformation of the multidrug transporter LmrP
per: del Alamo, Diego, et al.
Publicat: (2021)

The Multidrug Transporter LmrP Protein Mediates Selective Calcium Efflux
per: Schaedler, Theresia A., et al.
Publicat: (2012)

Energetics and Mechanism of Drug Transport Mediated by the Lactococcal Multidrug Transporter LmrP
per: Henk Bolhuis, et al.
Publicat: (1996)

Complexities of a protonatable substrate in measurements of Hoechst 33342 transport by multidrug transporter LmrP
per: Swain, Brendan M., et al.
Publicat: (2020)

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions
per: Nair, Asha V., et al.
Publicat: (2016)

Lipids modulate the conformational dynamics of a secondary multidrug transporter
per: Martens, Chloé, et al.
Publicat: (2016)

Lipids modulate the conformational dynamics of a secondary multidrug transporter
per: Chloé Martens, et al.
Publicat: (2016)

Basic Residues R260 and K357 Affect the Conformational Dynamics of the Major Facilitator Superfamily Multidrug Transporter LmrP
per: Wang, Wei, et al.
Publicat: (2012)

Broadly conserved Na(+)-binding site in the N-lobe of prokaryotic multidrug MATE transporters
per: Ficici, Emel, et al.
Publicat: (2018)

Lipid Composition Regulates the Orientation of Transmembrane Helices in HorA, an ABC Multidrug Transporter
per: Gustot, Adelin, et al.
Publicat: (2010)

Dynamic multidrug recognition by multidrug transcriptional repressor LmrR
per: Takeuchi, Koh, et al.
Publicat: (2014)

Dynamic multidrug recognition by multidrug transcriptional repressor LmrR
per: Koh Takeuchi, et al.
Publicat: (2014)

Conserved binding site in the N-lobe of prokaryotic MATE transporters suggests a role for Na(+) in ion-coupled drug efflux
per: Castellano, Steven, et al.
Publicat: (2021)

LmrR Is a Transcriptional Repressor of Expression of the Multidrug ABC Transporter LmrCD in Lactococcus lactis
per: Agustiandari, Herfita, et al.
Publicat: (2008)

LmrR Is a Transcriptional Repressor of Expression of the Multidrug ABC Transporter LmrCD in <i>Lactococcus lactis</i>
per: Herfita Agustiandari, et al.
Publicat: (2007)

Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition
per: Madoori, Pramod Kumar, et al.
Publicat: (2009)

Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition
per: P.K. Madoori, et al.
Publicat: (2008)

Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1
per: Daniel A.P. Gutmann, et al.
Publicat: (2009)

Emerging consensus on the mechanism of polyspecific substrate recognition by the multidrug transporter P-glycoprotein
per: Xia, Di, et al.
Publicat: (2019)

LmrS Is a Multidrug Efflux Pump of the Major Facilitator Superfamily from Staphylococcus aureus
per: Floyd, Jody L., et al.
Publicat: (2010)

Asymmetry of inverted-topology repeats in the AE1 anion exchanger suggests an elevator-like mechanism
per: Ficici, Emel, et al.
Publicat: (2017)

UNDERSTANDING POLYSPECIFICITY WITHIN THE SUBSTRATE-BINDING CAVITY OF THE HUMAN MULTIDRUG RESISTANCE P-GLYCOPROTEIN
per: Martinez, Lorena, et al.
Publicat: (2014)

Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity
per: Esser, Lothar, et al.
Publicat: (2017)

Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity
per: Lothar Esser, et al.
Publicat: (2016)

Understanding polyspecificity within the substrate‐binding cavity of the human multidrug resistance P‐glycoprotein
per: Lorena Martinez, et al.
Publicat: (2013)

Powering the ABC multidrug exporter LmrA: How nucleotides embrace the ion-motive force
per: Agboh, Kelvin, et al.
Publicat: (2018)

Bacillus subtilis LmrA Is a Repressor of the lmrAB and yxaGH Operons: Identification of Its Binding Site and Functional Analysis of lmrB and yxaGH
per: Yoshida, Ken-ichi, et al.
Publicat: (2004)

Principles of alternating access in multidrug and toxin extrusion (MATE) transporters
per: Claxton, Derek P., et al.
Publicat: (2021)

Serum PLR and LMR in Behçet's disease
per: Ying Jiang, et al.
Publicat: (2017)

Dynamic equilibrium on DNA defines transcriptional regulation of a multidrug binding transcriptional repressor, LmrR
per: Takeuchi, Koh, et al.
Publicat: (2017)

LmrS Is a Multidrug Efflux Pump of the Major Facilitator Superfamily from <i>Staphylococcus aureus</i>
per: Jody L. Floyd, et al.
Publicat: (2010)

Allosteric regulation of G protein–coupled receptor activity by phospholipids
per: Rosie Dawaliby, et al.
Publicat: (2015)

The molecular basis for a polyspecific antibody.
per: Wing, M G
Publicat: (1995)

Characterization of murine polyspecific monoamine transporters
per: Miura, Yamato, et al.
Publicat: (2017)

OCT1 Polyspecificity—Friend or Foe?
per: Meyer, Marleen J., et al.
Publicat: (2021)

Evidence of Calcium Signaling and Modulation of the LmrS Multidrug Resistant Efflux Pump Activity by Ca(2 +) Ions in S. aureus
per: Nava, Amy R., et al.
Publicat: (2020)

Structure, Dynamics, and Substrate-induced Conformational Changes of the Multidrug Transporter EmrE in Liposomes
per: Amadi, Sepan T., et al.
Publicat: (2010)