Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis

Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis

YAP1 is a transcriptional coactivator and the principal effector of the Hippo signaling pathway, which is causally implicated in human cancer. Several YAP1 gene fusions have been identified in various human cancers and identifying the essential components of this family of gene fusions has significa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Frank Szulzewsky, Sonali Arora, Pia Hoellerbauer, Claire King, Erica Nathan, Marina Chan, Patrick J. Cimino, Tatsuya Ozawa, Daisuke Kawauchi, Kristian W. Pajtler, Richard J. Gilbertson, Patrick J. Paddison, Valeri Vasioukhin, Taranjit S. Gujral, Eric C. Holland
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2020
Mynediad Ar-lein:https://doi.org/10.1101/gad.338681.120
http://genesdev.cshlp.org/content/34/15-16/1051.full.pdf
Tagiau: Ychwanegu Tag
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https://doi.org/10.1101/gad.338681.120
http://genesdev.cshlp.org/content/34/15-16/1051.full.pdf

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