The NSD2/WHSC1/MMSET methyltransferase prevents cellular senescence‐associated epigenomic remodeling
Abstract Senescent cells may possess the intrinsic programs of metabolic and epigenomic remodeling, but the molecular mechanism remains to be clarified. Using an RNAi‐based screen of chromatin regulators, we found that knockdown of the NSD2/WHSC1/MMSET methyltransferase induced cellular senescence t...
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Main Authors: | , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2020
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在线阅读: | https://doi.org/10.1111/acel.13173 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.13173 |
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