IgA dominates the early neutralizing antibody response to SARS-CoV-2

IgA dominates the early neutralizing antibody response to SARS-CoV-2

Abstract A major dogma in immunology has it that the IgM antibody response precedes secondary memory responses built on the production of IgG, IgA and, occasionaly, IgE. Here, we measured acute humoral responses to SARS-CoV-2, including the frequency of antibody-secreting cells and the presence of s...

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Main Authors: Delphine Sterlin, Alexis Mathian, Makoto Miyara, Audrey Mohr, François Anna, Laetitia Claër, Paul Quentric, Jehane Fadlallah, P. Ghillani, Cary Gunn, Rick Hockett, Sasi Mudumba, Amélie Guihot, Charles‐Édouard Luyt, Julien Mayaux, Alexandra Beurton, S. Fourati, Jean‐Marc Lacorte, Hans Yssel, Christophe Parizot, Karim Dorgham, Pierre Charneau, Zahir Amoura, Guy Gorochov
Format: Pré-impressão
Language:English
Published: 2020
Online Access:https://doi.org/10.1101/2020.06.10.20126532
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https://doi.org/10.1101/2020.06.10.20126532

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