Hypomethylation Causes MIR21 Overexpression in Tumors
miR-21 is an oncogenic microRNA (miRNA) that is upregulated in many solid tumors. However, the effect of MIR21 hypomethylation on miR-21 expression in tumors and the mechanism of miR-21 DNA demethylation remain unclear. In this study, we confirmed that the expression of miR-21 was significantly incr...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | angličtina |
| Vydáno: |
2020
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| On-line přístup: | https://doi.org/10.1016/j.omto.2020.05.011 https://www.cell.com/article/S2372770520300747/pdf |
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