Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity
Childhood acute lymphoblastic leukemia (cALL) is the most common pediatric cancer. It is characterized by bone marrow lymphoid precursors that acquire genetic alterations, resulting in disrupted maturation and uncontrollable proliferation. More than a dozen molecular subtypes of variable severity ca...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2020
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| 在線閱讀: | https://doi.org/10.1038/s41598-020-64929-x https://www.nature.com/articles/s41598-020-64929-x.pdf |
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