Sensing soluble uric acid by Naip1-Nlrp3 platform

Sensing soluble uric acid by Naip1-Nlrp3 platform

Summary The immune system can recognize microbes and sterile tissue damage. Among the damage-associated molecular patterns (DAMPs), uric acid is considered a major component which can trigger inflammation. It represents a breakpoint in the evolutionary history of humans as our ancestors lost the uri...

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Hlavní autoři: Tárcio Teodoro Braga, Mariana Rodrigues Davanso, Davi Mendes, Tiago Antônio de Souza, Anderson F. Brito, Mário Costa Cruz, Meire Ioshie Hiyane, Dhêmerson Souza de Lima, Vinícius Nunes Cordeiro Leal, Juliana de Fátima Giarola, Dênio Emanuel Pires Souto, Tomasz Próchnicki, Mario Lauterbach, Stellee Marcela Petris Biscaia, Rilton Alves de Freitas, Rui Curi, Alessandra Pontillo, Eicke Latz, Niels Olsen Saraiva Câmara
Médium: Pré-impressão
Jazyk:angličtina
Vydáno: 2020
On-line přístup:https://doi.org/10.1101/2020.05.15.077644
https://www.biorxiv.org/content/biorxiv/early/2020/05/15/2020.05.15.077644.full.pdf
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https://doi.org/10.1101/2020.05.15.077644
https://www.biorxiv.org/content/biorxiv/early/2020/05/15/2020.05.15.077644.full.pdf

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