Sensing soluble uric acid by Naip1-Nlrp3 platform
Summary The immune system can recognize microbes and sterile tissue damage. Among the damage-associated molecular patterns (DAMPs), uric acid is considered a major component which can trigger inflammation. It represents a breakpoint in the evolutionary history of humans as our ancestors lost the uri...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| 格式: | Pré-impressão |
| 語言: | 英语 |
| 出版: |
2020
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| 在線閱讀: | https://doi.org/10.1101/2020.05.15.077644 https://www.biorxiv.org/content/biorxiv/early/2020/05/15/2020.05.15.077644.full.pdf |
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