The Advent of CAR T-Cell Therapy for Lymphoproliferative Neoplasms: Integrating Research Into Clinical Practice

The Advent of CAR T-Cell Therapy for Lymphoproliferative Neoplasms: Integrating Research Into Clinical Practice

Research on CAR T cells has achieved enormous progress in recent years. After the impressive results obtained in relapsed and refractory B-cell acute lymphoblastic leukemia and aggressive B-cell lymphomas, two constructs, tisagenlecleucel and axicabtagene ciloleucel, were approved by FDA. The role o...

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Main Authors: Marco Cerrano, Marco Ruella, Miguel‐Angel Perales, Candida Vitale, Danilo Faraci, Luisa Giaccone, Marta Coscia, Molly Maloy, Miriam Sánchez‐Escamilla, Hesham Elsabah, Afraa M. Fadul, Enrico Maffini, Gianfranco Pittari, Benedetto Bruno
Format: Revisão
Language:English
Published: 2020
Online Access:https://doi.org/10.3389/fimmu.2020.00888
https://www.frontiersin.org/articles/10.3389/fimmu.2020.00888/pdf
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https://doi.org/10.3389/fimmu.2020.00888
https://www.frontiersin.org/articles/10.3389/fimmu.2020.00888/pdf

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