A phase 2 multicenter study of ublituximab, a novel glycoengineered anti-CD20 monoclonal antibody, in patients with relapsing forms of multiple sclerosis

Background: Ublituximab, a novel monoclonal antibody (mAb) targeting a unique epitope on the CD20 antigen, is glycoengineered for enhanced B-cell targeting through antibody-dependent cellular cytotoxicity (ADCC). Greater ADCC may allow lower doses and shorter infusion times versus other anti-CD20 mA...

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Autors principals: Edward Fox, Amy E. Lovett‐Racke, Matthew Gormley, Yue Liu, Maria Petracca, Sirio Cocozza, Richard Shubin, Sibyl Wray, Michael Weiss, Jenna A. Bosco, Sean A. Power, Koby Mok, Matilde Inglese
Format: Artigo
Idioma:anglès
Publicat: 2020
Accés en línia:https://doi.org/10.1177/1352458520918375
https://journals.sagepub.com/doi/pdf/10.1177/1352458520918375
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