Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

The clinical diagnosis of synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), is challenging, especially at an early disease stage, due to the heterogeneous and often non-specific clinical manifestations. The discovery of re...

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Main Authors: Marcello Rossi, Niccolò Candelise, Simone Baiardi, Sabina Capellari, Giulia Giannini, Christina D. Orrù, Elena Antelmi, Angela Mammana, Andrew G. Hughson, Giovanna Calandra‐Buonaura, Anna Ladogana, Giuseppe Plazzi, Pietro Cortelli, Byron Caughey, Piero Parchi
Format: Artigo
Language:English
Published: 2020
Online Access:https://doi.org/10.1007/s00401-020-02160-8
https://link.springer.com/content/pdf/10.1007/s00401-020-02160-8.pdf
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