Progressive multifocal leukoencephalopathy in a patient post allo-HCT successfully treated with JC virus specific donor lymphocytes
Abstract Background Progressive multifocal leukoencephalopathy is a demyelinating CNS disorder. Reactivation of John Cunningham virus leads to oligodendrocyte infection with lysis and consequent axonal loss due to demyelination. Patients usually present with confusion and seizures. Late diagnosis an...
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2020
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在线阅读: | https://doi.org/10.1186/s12967-020-02337-5 https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-020-02337-5.pdf |
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