Progressive multifocal leukoencephalopathy in a patient post allo-HCT successfully treated with JC virus specific donor lymphocytes

Progressive multifocal leukoencephalopathy in a patient post allo-HCT successfully treated with JC virus specific donor lymphocytes

Abstract Background Progressive multifocal leukoencephalopathy is a demyelinating CNS disorder. Reactivation of John Cunningham virus leads to oligodendrocyte infection with lysis and consequent axonal loss due to demyelination. Patients usually present with confusion and seizures. Late diagnosis an...

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Main Authors: Maximilian Steinhardt, Eliza Wiercinska, Manh Van Pham, Götz Ulrich Grigoleit, Alessandro Mazzoni, Matteo C. Da Vià, Xiang Zhou, Katharina Meckel, Katharina Nickel, Johannes Duell, Franziska Krummenast, Sabrina Kraus, Cathy Hopkinson, Benedikt Weißbrich, Wolfgang Müllges, Guido Stoll, K. Martin Kortüm, Hermann Einsele, Halvard Bönig, Leo Rasche
Format: Artigo
Sprog:engelsk
Udgivet: 2020
Online adgang:https://doi.org/10.1186/s12967-020-02337-5
https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-020-02337-5.pdf
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https://doi.org/10.1186/s12967-020-02337-5
https://translational-medicine.biomedcentral.com/track/pdf/10.1186/s12967-020-02337-5.pdf

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