Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies

Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies

Hypoxia promotes renal damage and progression of chronic kidney disease (CKD). The erythrocyte is the only cell type for oxygen (O2) delivery. Sphingosine 1-phosphate (S1P)-a highly enriched biolipid in erythrocytes-is recently reported to be induced under high altitude in normal humans to enhance O...

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Huvudupphovsmän: Tingting Xie, Chang‐Han Chen, Zhangzhe Peng, Benjamin C. Brown, Julie A. Reisz, Ping Xu, Zhen Zhou, Anren Song, Yujin Zhang, Mikhail Bogdanov, Rodney E. Kellems, Angelo D’Alessandro, Weiru Zhang, Yang Xia
Materialtyp: Artigo
Språk:engelska
Publicerad: 2020
Länkar:https://doi.org/10.1161/circresaha.119.316298
https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.119.316298
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https://doi.org/10.1161/circresaha.119.316298
https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.119.316298

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