Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies

Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies

Hypoxia promotes renal damage and progression of chronic kidney disease (CKD). The erythrocyte is the only cell type for oxygen (O2) delivery. Sphingosine 1-phosphate (S1P)-a highly enriched biolipid in erythrocytes-is recently reported to be induced under high altitude in normal humans to enhance O...

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Auteurs principaux: Tingting Xie, Chang‐Han Chen, Zhangzhe Peng, Benjamin C. Brown, Julie A. Reisz, Ping Xu, Zhen Zhou, Anren Song, Yujin Zhang, Mikhail Bogdanov, Rodney E. Kellems, Angelo D’Alessandro, Weiru Zhang, Yang Xia
Format: Artigo
Langue:anglais
Publié: 2020
Accès en ligne:https://doi.org/10.1161/circresaha.119.316298
https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.119.316298
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https://doi.org/10.1161/circresaha.119.316298
https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.119.316298

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