Kidney tissue hypoxia dictates T cell–mediated injury in murine lupus nephritis
HIF-1 dictates effector function of infiltrating T cells in lupus, causing tissue damage that can be abrogated by its blockade in murine models.
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2020
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| Accesso online: | https://doi.org/10.1126/scitranslmed.aay1620 |
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| Riassunto: | HIF-1 dictates effector function of infiltrating T cells in lupus, causing tissue damage that can be abrogated by its blockade in murine models. |
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