Irisin counteracts high glucose and fatty acid-induced cytotoxicity by preserving the AMPK-insulin receptor signaling axis in C2C12 myoblasts
Irisin, a newly identified myokine, is critical to modulating body metabolism and biological homeostasis. However, whether irisin protects the skeletal muscles against metabolic stresses remains unknown. In this study, we determine the effect of irisin on high glucose and fatty acid-induced damages...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | английский |
| Опубликовано: |
2020
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| Online-ссылка: | https://doi.org/10.1152/ajpendo.00219.2019 https://journals.physiology.org/doi/pdf/10.1152/ajpendo.00219.2019 |
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