Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons
Abstract The molecular processes underlying the aging-related decline in cognitive performance and memory observed in humans are poorly understood. Studies in rodents have shown a decrease in N-methyl-D-aspartate receptors (NMDARs) that contain the GluN2B subunit in aging synapses, and this decrease...
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Autori principali: | , , , , , , , , , , , , |
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Natura: | Artigo |
Lingua: | inglese |
Pubblicazione: |
2020
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Accesso online: | https://doi.org/10.1093/cercor/bhaa052 |
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