Optogenetic intervention of seizures improves spatial memory in a mouse model of chronic temporal lobe epilepsy

Abstract Objective To determine if closed‐loop optogenetic seizure intervention, previously shown to reduce seizure duration in a well‐established mouse model chronic temporal lobe epilepsy (TLE), also improves the associated comorbidity of impaired spatial memory. Methods Mice with chronic, spontan...

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Main Authors: Hannah K. Kim, Tilo Gschwind, Theresa Nguyen, Anh Bui, Sylwia Felong, Kristen Ampig, David Y. Suh, Annie Vogel Ciernia, Marcelo A. Wood, Iván Soltész
格式: Artigo
語言:英语
出版: 2020
在線閱讀:https://doi.org/10.1111/epi.16445
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