ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway
Abstract The accumulation of damaged mitochondria causes the death of dopaminergic neurons. The Parkin-mediated mitophagy pathway functions to remove these mitochondria from cells. Targeting this pathway represents a therapeutic strategy for several neurodegenerative diseases, most notably Parkinson...
-д хадгалсан:
Үндсэн зохиолчид: | , , , , , , |
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Формат: | Artigo |
Хэл сонгох: | англи |
Хэвлэсэн: |
2020
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Онлайн хандалт: | https://doi.org/10.1038/s41467-019-13781-3 https://www.nature.com/articles/s41467-019-13781-3.pdf |
Шошгууд: |
Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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