ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway
Abstract The accumulation of damaged mitochondria causes the death of dopaminergic neurons. The Parkin-mediated mitophagy pathway functions to remove these mitochondria from cells. Targeting this pathway represents a therapeutic strategy for several neurodegenerative diseases, most notably Parkinson...
Salvato in:
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2020
|
| Accesso online: | https://doi.org/10.1038/s41467-019-13781-3 https://www.nature.com/articles/s41467-019-13781-3.pdf |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|