ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway
Abstract The accumulation of damaged mitochondria causes the death of dopaminergic neurons. The Parkin-mediated mitophagy pathway functions to remove these mitochondria from cells. Targeting this pathway represents a therapeutic strategy for several neurodegenerative diseases, most notably Parkinson...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2020
|
| 在线阅读: | https://doi.org/10.1038/s41467-019-13781-3 https://www.nature.com/articles/s41467-019-13781-3.pdf |
| 标签: |
添加标签
没有标签, 成为第一个标记此记录!
|