High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer

DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC). Its DNA amplification is often part of the targeted DNA-sequencing p...

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Main Authors: Eriko Katsuta, Li Yan, Takashi Takeshita, Kerry-Ann McDonald, Subhamoy Dasgupta, Mateusz Opyrchal, Kazuaki Takabe
格式: Artigo
语言:英语
出版: 2019
在线阅读:https://doi.org/10.3390/ijms21010217
https://www.mdpi.com/1422-0067/21/1/217/pdf?version=1577502639
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