Repression of phagocytosis by human CD33 is not conserved with mouse CD33
Abstract CD33 is an immunomodulatory receptor linked to Alzheimer’s disease (AD) susceptibility via regulation of phagocytosis in microglia. Divergent features between human CD33 (hCD33) and murine CD33 (mCD33) include a unique transmembrane lysine in mCD33 and cytoplasmic tyrosine in hCD33. The fun...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2019
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| 在线阅读: | https://doi.org/10.1038/s42003-019-0698-6 https://www.nature.com/articles/s42003-019-0698-6.pdf |
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