Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway

Obesity-related insulin resistance and high fatty acid concentrations occur during the development of type 2 diabetes mellitus. The role of high concentrations of plasma-free fatty acids is not fully understood. In this study, palmitic acid (PA, 0.8 mM for 24 h) induced the expression of miR-221 tha...

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Main Authors: Fang Huang, Jie Chen, Jingwen Wang, Pingping Zhu, Wenting Lin
格式: Artigo
语言:英语
出版: 2019
在线阅读:https://doi.org/10.1155/2019/8171989
https://downloads.hindawi.com/journals/bmri/2019/8171989.pdf
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