Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians
Supercentenarians, people who have reached 110 y of age, are a great model of healthy aging. Their characteristics of delayed onset of age-related diseases and compression of morbidity imply that their immune system remains functional. Here we performed single-cell transcriptome analysis of 61,202 p...
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Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | inglés |
Publicado: |
2019
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Acceso en liña: | https://doi.org/10.1073/pnas.1907883116 https://www.pnas.org/content/pnas/116/48/24242.full.pdf |
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