Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians

Supercentenarians, people who have reached 110 y of age, are a great model of healthy aging. Their characteristics of delayed onset of age-related diseases and compression of morbidity imply that their immune system remains functional. Here we performed single-cell transcriptome analysis of 61,202 p...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Kosuke Hashimoto, Tsukasa Kouno, Tomokatsu Ikawa, Norihito Hayatsu, Yurina Miyajima, Haruka Yabukami, Tommy Terooatea, Takashi Sasaki, Takahiro Suzuki, Matthew Valentine, Giovanni Pascarella, Yasushi Okazaki, Harukazu Suzuki, Jay W. Shin, Aki Minoda, Ichiro Taniuchi, Hideyuki Okano, Yasumichi Arai, Nobuyoshi Hirose, Piero Carninci
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2019
Online toegang:https://doi.org/10.1073/pnas.1907883116
https://www.pnas.org/content/pnas/116/48/24242.full.pdf
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!