Peritransplant eculizumab does not prevent delayed graft function in deceased donor kidney transplant recipients: Results of two randomized controlled pilot trials

Peritransplant eculizumab does not prevent delayed graft function in deceased donor kidney transplant recipients: Results of two randomized controlled pilot trials

Animal models and observational human data indicate that complement, including C5a, pathogenically participates in ischemia reperfusion (IR) injury that manifests as delayed graft function (DGF) following deceased donor kidney transplantation. We report on the safety/efficacy of anti-C5 monoclonal a...

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Hauptverfasser: Bernd Schröppel, Enver Akalin, Mukta Baweja, Roy D. Bloom, Sander Florman, Michael J. Goldstein, Brandy Haydel, Donald E. Hricik, Sanjay Kulkarni, Matthew H. Levine, Anita Mehrotra, Anup Patel, Emilio D. Poggio, Lloyd E. Ratner, Ron Shapiro, Peter S. Heeger
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2019
Online-Zugang:https://doi.org/10.1111/ajt.15580
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ajt.15580
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https://doi.org/10.1111/ajt.15580
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ajt.15580

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