Effect of the inhaled PDE4 inhibitor CHF6001 on biomarkers of inflammation in COPD

CHF6001 is a novel inhaled phosphodiesterase-4 inhibitor. This Phase IIa study assessed the effects of CHF6001 on markers of inflammation in induced sputum and blood in patients with chronic obstructive pulmonary disease (COPD). This was a multicentre, three-period (each 32 days), three-way, placebo...

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Hlavní autoři: Dave Singh, Kai Michael Beeh, Brendan Colgan, Oliver Kornmann, Brian Leaker, Henrik Watz, Germano Lucci, Silvia Geraci, Aida Emirova, Mirco Govoni, Marie Anna Nandeuil
Médium: Artigo
Jazyk:angličtina
Vydáno: 2019
On-line přístup:https://doi.org/10.1186/s12931-019-1142-7
https://respiratory-research.biomedcentral.com/track/pdf/10.1186/s12931-019-1142-7
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