BIN1 favors the spreading of Tau via extracellular vesicles

Abstract Despite Bridging INtegrator 1 ( BIN1 ) being the second most statistically-significant locus associated to Late Onset Alzheimer’s Disease, its role in disease pathogenesis remains to be clarified. As reports suggest a link between BIN1, Tau and extracellular vesicles, we investigated whethe...

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Hlavní autoři: Andrea Crotti, Hameetha Rajamohamend Sait, Kathleen M. McAvoy, Karol Estrada, Ayla Ergün, Suzanne Szak, Galina Marsh, Luke Jandreski, Michael Peterson, Taylor L. Reynolds, Isin Dalkilic-Liddle, Andrew Cameron, Ellen Cahir-McFarland, Richard M. Ransohoff
Médium: Artigo
Jazyk:angličtina
Vydáno: 2019
On-line přístup:https://doi.org/10.1038/s41598-019-45676-0
https://www.nature.com/articles/s41598-019-45676-0.pdf
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