Site-specifically labeled <sup>89</sup>Zr-DFO-trastuzumab improves immuno-reactivity and tumor uptake for immuno-PET in a subcutaneous HER2-positive xenograft mouse model

Antibody-based PET tracers are exceptionally well-suited for determination of the in vivo biodistribution and quantification of therapeutic antibodies. The continued expansion in antibody-based therapeutics has accordingly driven the development towards more robust conjugation strategies in order to...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Lotte K. Kristensen, Camilla L. Christensen, Mette Munk Jensen, Brian Agnew, Christina Schjöth-Frydendahl, Andreas Kjær, Carsten H. Nielsen
Hōputu: Artigo
Reo:Ingarihi
I whakaputaina: 2019
Urunga tuihono:https://doi.org/10.7150/thno.32883
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