Local and global chromatin interactions are altered by large genomic deletions associated with human brain development
Large copy number variants (CNVs) in the human genome are strongly associated with common neurodevelopmental, neuropsychiatric disorders such as schizophrenia and autism. Here we report on the epigenomic effects of the prominent large deletion CNVs on chromosome 22q11.2 and on chromosome 1q21.1. We...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | inglese |
| Pubblicazione: |
2018
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| Accesso online: | https://doi.org/10.1038/s41467-018-07766-x https://www.nature.com/articles/s41467-018-07766-x.pdf |
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