Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters

Enzymatic stereodivergent synthesis to access all possible product stereoisomers bearing multiple stereocenters is relatively undeveloped, although enzymes are being increasingly used in both academic and industrial areas. When two stereocenters and thus four stereoisomeric products are involved, ob...

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Main Authors: Jian Xu, Yixin Cen, Warispreet Singh, Jiajie Fan, Lian Wu, Xianfu Lin, Jiahai Zhou, Meilan Huang, Manfred T. Reetz, Qi Wu
格式: Artigo
语言:英语
出版: 2019
在线阅读:https://doi.org/10.1021/jacs.9b02709
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