Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex

Abstract Human activity caused dramatic population declines in many wild species. The resulting bottlenecks have a profound impact on the genetic makeup of a species with unknown consequences for health. A key genetic factor for species survival is the evolution of deleterious mutation load, but how...

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Main Authors: Christine Grossen, Frédéric Guillaume, Lukas F. Keller, Daniel Croll
格式: Pré-impressão
語言:英语
出版: 2019
在線閱讀:https://doi.org/10.1101/605147
https://www.biorxiv.org/content/biorxiv/early/2019/12/15/605147.full.pdf
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