Osteopontin lung gene expression is a marker of disease severity in pulmonary arterial hypertension
ABSTRACT Background and objective Osteopontin (OPN) is a pleiotropic cytokine involved in the proliferation of pulmonary artery smooth muscle cells (PA‐SMC). OPN is upregulated in the lungs of patients with pulmonary hypertension (PH) associated with pulmonary fibrosis, suggesting that the lung is a...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2019
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| 在线阅读: | https://doi.org/10.1111/resp.13557 |
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