Remodeling the cancer epigenome: mutations in the SWI/SNF complex offer new therapeutic opportunities
Introduction: Cancer genome sequencing studies have discovered mutations in members of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodeling complex in nearly 25% of human cancers. The SWI/SNF complex, first discovered in S. cerevisiae, shows strong conservation from yeast to Drosophila...
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| Main Authors: | , , , , |
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| 格式: | Revisão |
| 语言: | 英语 |
| 出版: |
2019
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| 在线阅读: | https://doi.org/10.1080/14737140.2019.1605905 |
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