Repeated clinical malaria episodes are associated with modification of the immune system in children

Repeated clinical malaria episodes are associated with modification of the immune system in children

There are over 200 million reported cases of malaria each year, and most children living in endemic areas will experience multiple episodes of clinical disease before puberty. We set out to understand how frequent clinical malaria, which elicits a strong inflammatory response, affects the immune sys...

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Main Authors: Yaw Bediako, Rhys Adams, Adam J. Reid, John Joseph Valletta, Francis M. Ndungu, Jan Sodenkamp, Jedidah Mwacharo, Joyce Ngoi, Domtila Kimani, Oscar Kai, Juliana Wambua, George Nyangweso, Etienne P. de Villiers, Mandy Sanders, Magda E. Lotkowska, Jingwen Lin, Sarah Manni, John Addy, Mario Recker, Chris Newbold, Matthew Berriman, Philip Bejon, Kevin Marsh, Jean Langhorne
Format: Artigo
Language:English
Published: 2019
Online Access:https://doi.org/10.1186/s12916-019-1292-y
https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-019-1292-y
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https://doi.org/10.1186/s12916-019-1292-y
https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-019-1292-y

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