Vesicular Glutamatergic Transmission in Noise-Induced Loss and Repair of Cochlear Ribbon Synapses

Noise-induced excitotoxicity is thought to depend on glutamate. However, the excitotoxic mechanisms are unknown, and the necessity of glutamate for synapse loss or regeneration is unclear. Despite absence of glutamatergic transmission from cochlear inner hair cells in mice lacking the vesicular glut...

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Auteurs principaux: Kyunghee X. Kim, Shelby Payne, Aizhen Yang-Hood, Song-Zhe Li, Bethany Davis, Jason Carlquist, Babak V-Ghaffari, Jay A. Gantz, Dorina Kallogjeri, James A. J. Fitzpatrick, Kevin K. Ohlemiller, Keiko Hirose, Mark A. Rutherford
Format: Artigo
Langue:anglais
Publié: 2019
Accès en ligne:https://doi.org/10.1523/jneurosci.2228-18.2019
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