The renin-angiotensin system: going beyond the classical paradigms
Thirty years ago, a novel axis of the renin-angiotensin system (RAS) was unveiled by the discovery of angiotensin- (1-7) [ANG-(1-7)] generation in vivo. Later, angiotensin-converting enzyme 2 (ACE2) was shown to be the main mediator of this reaction, and Mas was found to be the receptor for the hept...
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| Hlavní autoři: | , , , , , |
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| Médium: | Revisão |
| Jazyk: | angličtina |
| Vydáno: |
2019
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| On-line přístup: | https://doi.org/10.1152/ajpheart.00723.2018 |
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